Eukaryotic initiation factor 2α phosphorylation is required for B-cell maturation and function in mice
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چکیده
Original Articles haematologica | 2011; 96(9) 1261
منابع مشابه
Eukaryotic initiation factor 2alpha phosphorylation is required for B-cell maturation and function in mice.
BACKGROUND The control of translation initiation is a crucial component in the regulation of gene expression. The eukaryotic initiation factor 2α (eIF2α) mediates binding of the initiator transfer-messenger-RNA to the AUG initiation codon, and thus controls a rate-limiting step in translation initiation. Phosphorylation of eIF2α at serine 51 is linked to cellular stress response and attenuates ...
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تاریخ انتشار 2011